Dr. Dennis Slamon: The Search for a Cure for Breast Cancer
Dr. Dennis Slamon has devoted his life to finding treatments for breast cancer. His drug, Herceptin, has saved more than 400,000 lives. myLifetime.com sat down with Dr. Slamon to talk about his extraordinary work and the movie based on his life. “Living Proof” premieres Saturday, October 18 at 9 pm et/pt.
Topics: breast cancer, harry connick jr., lilly tartikoff More
The story is about your research. How did the movie come to be, as far as your involvement?
Robert Bazell's book is all about the whole development of the drug. I think that the story is about a lot of people who are involved in that, including and most importantly the patients who were involved in the testing of that drug. I think, in that sense, it's a broader story than beyond just me.
How has this drug changed women's lives since its introduction?
Since the introduction of the drug, it's had a dramatic response for the women who respond to it. Not all women respond, but the ones who do seem to do very well, and we now have long-term survivors in this subtype, which we never had before. In Bob's book and in the movie, they talk about a couple of patients who really did very well, who are out now 11 or 12 years with no evidence of the disease. So we think it's been very effective. That's gratifying.
How is this movie helping to bring awareness to alternate treatments for cancer?
I think "Living Proof" does a good job of showing patients new things and researching new therapeutic approaches. There's a lot going on in clinical research. Unfortunately, in the world of cancer, maybe 3 to 4 percent of patients go on clinical trials when maybe 20 percent or more are eligible. I think the public being aware of the fact that there are these things out there, testing these new and hopefully effective treatments, is an option. And I think "Living Proof" accurately portrayed that.
Do you recommend breast cancer patients signing up for clinical trials?
I think all patients who have breast cancer — all patients who have any kind of cancer — should look at clinical trials. Patients never get anything less than the best available care and frequently get something that may be better, just by virtue of being on a clinical trial and having to be monitored so closely and so carefully. So I think there are a lot of advantages to seriously looking at a clinical trial and participating. And I think that would be a good thing if that came out of "Living Proof."
Why do you hope people will watch "Living Proof"?
The positive thing in all of this for me in terms of having "Living Proof" out there is that it's going to give the public a view that there is effective research going on and that they can be participants, both actively and just a step back in terms of support. The portrayal of the patients that got involved in the clinical trial, the portrayal of the advocacy group that got involved on the federal level and at the industry level is accurate, and in that sense, the movie is a real success.

comments
Thank you for working endlessly to develop Herceptin. I was diagnosed with bilateral breast cancer in 2004 at the age of 38. I had 2 different types at the same time. The tumor in my left breast was HER2 positive. I had no lymph node involvment. I had a bilateral mastectomy and 8 treatments of traditional chemo. Then I was asked to take Herceptin. I was the first person in the county that I live in to take Herceptin without an active tumor. I was apprehensvie at first but now I am glad that I trusted my Oncologist and glad that she trusted your drug. I am now 4 1/2 years cancer free! Thanks to you and all those who helped you for giving so much time and dedication to this. May God bless you, your family, and your work.
Stephanie McMurray
Your devotion to finding a cure for this dread disease has to have taken a lot of your time. I can't thank you enough for
all of the lives you have saved, including my own.
I was diagnosed in February of 1999 with Stage III HER2 + Breast cancer with 15 out of 30 lymph node involvement.
I had a mastectomy, eight rounds of chemotherapy and 32 days of radiation. a year and a half later I had my first recurrence, more chemotherapy this time, my doctor also started me on herceptin.
I did have three more recurrences while receiving herceptin
last one being 2004. I have been in remission and presently, still receiving your wonder drug. I thank God every day. For without herceptin I would not be here, 10 years later, after being diagnosed with such an aggressive cancer. Family & friends are amazed at my progress and how well I am doing.
Thank you again, Dr Slamon, for your dedication and brilliant mind.
Carole, another survivor thanks to herceptin...........
I cried my eyes out in the final scenes when all the woman were in the stadium and more and more women were in the stands. It was great. My partner is still in the stands and doing great today because of Dr. Salman.
thank you very much
I do not have breast cancer i actually don't know anybody who does. But you have inspired me to learn more about the subject. I am doing a report on it and I think that you are a miracle worker. Thank you for helping all of those women.
After 4 quimotherapy and mastectomy following 2 quimos and radotherapy i'm fine! I'm still having herceptin and i call it: MY GOLDEN DROPS!!!!!!!!!! It is VERY VERY precious!!!!! THANK YOU AND GOD BLESS YOU for your work and grace! thank you for my life!!! ALL THE BEST FOR YOUR LIFE!!!!! roberta rees,
rrees@gmx.de